- Click on the title of each paper to access MedLine abstract at NLM site
Constipation

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Agrawal A, Houghton LA, Lea R, Morris J, Reilly B, Whorwell PJ. Bloating and Distention in Irritable Bowel Syndrome: The Role of Visceral Sensation. Gastroenterology. 2008 Mar 8.

Lopes AC, Victoria CR. [Fiber intake and colonic transit time in functional constipated patients.] Arq Gastroenterol. 2008 Jan-Mar;45(1):58-63. Portuguese.

Lacerda-Filho A, Lima MJ, Magalhães MF, Paiva RD, Cunha-Melo JR. Chronic constipation - the role of clinical assessment and colorectal physiologic tests to obtain an etiologic diagnosis. Arq Gastroenterol. 2008 Mar;45(1):50-57.

Bratten JR, Spanier J, Jones MP. Lactulose breath testing does not discriminate patients with irritable bowel syndrome from healthy controls. Am J Gastroenterol. 2008 Apr;103(4):958-63.

Gladman MA, Knowles CH. Novel concepts in the diagnosis, pathophysiology and management of idiopathic megabowel. Colorectal Dis. 2008 Mar 18.

Varma MG, Hart SL, Brown JS, Creasman JM, Van Den Eeden SK, Thom DH. Obstructive Defecation in Middle-aged Women. Dig Dis Sci. 2008 Mar 14

Holzer B, Rosen HR, Novi G, Ausch C, Hölbling N, Hofmann M, Schiessel R. Sacral nerve stimulation in patients with severe constipation. Dis Colon Rectum. 2008 May;51(5):524-30.

van den Esschert JW, van Geloven AA, Vermulst N, Groenedijk A, de Wit LT, Gerhards MF. Laparoscopic ventral rectopexy for obstructed defecation syndrome. Surg Endosc. 2008 Mar 5.

Del Popolo G, Mosiello G, Pilati C, Lamartina M, Battaglino F, Buffa P, Redaelli T, Lamberti G, Menarini M, Di Benedetto P, De Gennaro M. Treatment of neurogenic bowel dysfunction using transanal irrigation: a multicenter Italian study. Spinal Cord. 2008 Mar 4.

Mowatt G, Glazener C, Jarrett M. Sacral nerve stimulation for fecal incontinence and constipation in adults: a short version Cochrane review. Neurourol Urodyn. 2008;27(3):155-61. Review.

Meurette G, Siproudhis L, Regenet N, Frampas E, Proux M, Lehur PA. Poor symptomatic relief and quality of life in patients treated for "solitary rectal ulcer syndrome without external rectal prolapse". Int J Colorectal Dis. 2008 May;23(5):521-6.

Peppas G, Alexiou VG, Mourtzoukou E, Falagas ME. Epidemiology of constipation in Europe and Oceania: a systematic review. BMC Gastroenterol. 2008 Feb 12;8:5. Review.

Eltringham MT, Khan U, Bain IM, Wooff DA, Mackie A, Jefferson E, Yiannakou Y. Functional defecation disorder as a clinical subgroup of chronic constipation: Analysis of symptoms and physiological parameters. Scand J Gastroenterol. 2008 Mar;43(3):262-9.

McCrea GL, Miaskowski C, Stotts NA, Macera L, Hart SA, Varma MG. Review article: self-report measures to evaluate constipation. Aliment Pharmacol Ther. 2008 Apr;27(8):638-48.

Shi J, Tong Y, Shen JG, Li HX. Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: a systematic review. World J Gastroenterol. 2008 Jan 21;14(3):454-62.

Varma MG, Wang JY, Berian JR, Patterson TR, McCrea GL, Hart SL. The constipation severity instrument: a validated measure. Dis Colon Rectum. 2008 Feb;51(2):162-72.

Gagliardi G, Pescatori M, Altomare DF, Binda GA, Bottini C, Dodi G, Filingeri V, Milito G, Rinaldi M, Romano G, Spazzafumo L, Trompetto M; Italian Society of Colo-Rectal Surgery (SICCR). Results, outcome predictors, and complications after stapled transanal rectal resection for obstructed defecation. Dis Colon Rectum. 2008 Feb;51(2):186-95; discussion 195.

Ponce J, Martínez B, Fernández A, Ponce M, Bastida G, Plá E, Garrigues V, Ortiz V. Constipation during pregnancy: a longitudinal survey based on self-reported symptoms and the Rome II criteria. Eur J Gastroenterol Hepatol. 2008 Jan;20(1):56-61.

Feng Y, Jianjiang L. Functional outcomes of two types of subtotal colectomy for slow-transit constipation: ileosigmoidal anastomosis and cecorectal anastomosis. Am J Surg. 2008 Jan;195(1):73-7.

Zarate N, Knowles CH, Newell M, Garvie NW, Gladman MA, Lunniss PJ, Scott SM. In patients with slow transit constipation, the pattern of colonic transit delay does not differentiate between those with and without impaired rectal evacuation. Am J Gastroenterol. 2008 Feb;103(2):427-34.

Pinedo G, León F, Molina ME, Soto G, López F, Zúñiga A. A novel surgical approach to slow-transit constipation: report of two cases. Dis Colon Rectum. 2008 Jan;51(1):139-41.

Agrawal A, Whorwell PJ. Review article: abdominal bloating and distension in functional gastrointestinal disorders--epidemiology and exploration of possible mechanisms. Aliment Pharmacol Ther. 2008 Jan 1;27(1):2-10.

Danjo K, Sakamoto J, Iwane S, Tamura K, Nakaji S, Fukuda S, Murakami H, Shimoyama T, Takahashi I, Umeda T. Effects of cellulose supplementation on fecal consistency and fecal weight. Dig Dis Sci. 2008 Mar;53(3):712-8.

Altomare DF, Spazzafumo L, Rinaldi M, Dodi G, Ghiselli R, Piloni V. Set-up and statistical validation of a new scoring system for obstructed defaecation syndrome. Colorectal Dis. 2008 Jan;10(1):84-8.

Cazemier M, Felt-Bersma RJ, Mulder CJ. Anal plugs and retrograde colonic irrigation are helpful in fecal incontinence or constipation.  

Vierhout ME. [The end to the myth that hysterectomy has negative effects on the function of pelvic organs. Ned Tijdschr Geneeskd. 2007 Jun 2;151(22):1214-6. Dutch.

Di Palma JA, Cleveland MV, McGowan J, Herrera JL.  A Randomized, Multicenter Comparison of Polyethylene Glycol Laxative and Tegaserod in Treatment of Patients With Chronic Constipation. Am J Gastroenterol. 2007 Jun 15;

Zangaglia R, Martignoni E, Glorioso M, Ossola M, Riboldazzi G, Calandrella D, Brunetti G, Pacchetti C.  Macrogol for the treatment of constipation in Parkinson's disease. A randomized placebo-controlled study. Mov Disord. 2007 Jun 12;22(9):1239-

Iannelli A, Piche T, Dainese R, Fabiani P, Tran A, Mouiel J, Gugenheim J.  Long-term results of subtotal colectomy with cecorectal anastomosis for isolated colonic inertia.
World J Gastroenterol. 2007 May 14;13(18):2590-5.

Cowlam S, Watson C, Elltringham M, Bain I, Barrett P, Green S, Yiannakou Y.  Percutaneous endoscopic colostomy of the left side of the colon. Gastrointest Endosc. 2007 Jun;65(7):1007-14.

Di Stefano M, Miceli E, Mazzocchi S, Tana P, Missanelli A, Corazza GR.  Effect of Tegaserod on Recto-Sigmoid Tonic and Phasic Activity in Constipation-Predominant Irritable Bowel Syndrome. Am J Gastroenterol. 2007 May 23;

Evangelista S.  Drug evaluation: Pumosetrag for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
Curr Opin Investig Drugs. 2007 May;8(5):416-22. Review.

Ambizas EM, Ginzburg R.  Lubiprostone: a chloride channel activator for treatment of chronic constipation.
Ann Pharmacother. 2007 Jun;41(6):957-64.

Johanson JF, Ueno R.  Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: a double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety. Aliment Pharmacol Ther. 2007 Jun 1;25(11):1351-61.

Wulkow R, Vix JM, Schuijt C, Peil H, Kamm MA, Jordan C.  Randomised, placebo-controlled, double-blind study to investigate the efficacy and safety of the acute use of sodium picosulphate in patients with chronic constipation. Int J Clin Pract. 2007 Jun;61(6):944-50.

Pescatori M, Spyrou M, Pulvirenti d'Urso A.  A prospective evaluation of occult disorders in obstructed defecation using the 'iceberg diagram'. Colorectal Dis. 2007 Jun;9(5):452-6.

Slawik S, Soulsby R, Carter H, Payne H, Dixon AR.  Laparoscopic ventral rectopexy, posterior colporrhaphy and vaginal sacrocolpopexy for the treatment of recto-genital prolapse and mechanical outlet obstruction. Colorectal Dis. 2007 May 10;

Wong SW, Lubowski DZ.  Slow-transit constipation: evaluation and treatment. ANZ J Surg. 2007 May;77(5):320-8. Review.

Zeng J, Zuo XL, Li YQ, Wei W, Lv GP.  Tegaserod for dyspepsia and reflux symptoms in patients with chronic constipation: an exploratory open-label study. Eur J Clin Pharmacol. 2007 Jun;63(6):529-536.

Pare P, Bridges R, Champion MC, Ganguli SC, Gray JR, Irvine EJ, Plourde V, Poitras P, Turnbull GK, Moayyedi P, Flook N, Collins SM.  Recommendations on chronic constipation (including constipation associated with irritable bowel syndrome) treatment.
Can J Gastroenterol. 2007 Apr;21 Suppl B:3B-22B.

Altomare DF, Spazzafumo L, Rinaldi M, Dodi G, Ghiselli R, Piloni V.  Set-up and statistical validation of a new scoring system for obstructed defaecation syndrome. Colorectal Dis. 2007 Apr 18;

Biyani D, Barrow E, Hodson P, Watson AJ, Maclennan I.  Endoscopically placed caecostomy buttons: a trial ACE procedure. Colorectal Dis. 2007 May;9(4):373-6.  

Lundin E, Graf W, Garske U, Nilsson S, Maripuu E, Karlbom U. Segmental colonic transit studies: comparison of a radiological and a scintigraphic method. Colorectal Dis. 2007 May;9(4):344-51.

Kienzle-Horn S, Vix JM, Schuijt C, Peil H, Jordan CC, Kamm MA.  Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation. Curr Med Res Opin. 2007 Apr;23(4):691-9.

Heymen S, Scarlett Y, Jones K, Ringel Y, Drossman D, Whitehead WE.  Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. Dis Colon Rectum. 2007 Apr;50(4):428-41.

Gladman MA, Dvorkin LS, Scott SM, Lunniss PJ, Williams NS.  A novel technique to identify patients with megarectum. Dis Colon Rectum. 2007 May;50(5):621-9.

Murakami K, Sasaki S, Okubo H, Takahashi Y, Hosoi Y, Itabashi M; Freshmen in Dietetic Courses Study II Group.  Association between dietary fiber, water and magnesium intake and functional constipation among young Japanese women. Eur J Clin Nutr. 2007 May;61(5):616-22.

Dipalma JA, Cleveland MV, McGowan J, Herrera JL. A Randomized, Multicenter, Placebo-Controlled Trial of Polyethylene Glycol Laxative for Chronic Treatment of Chronic Constipation. Am J Gastroenterol. 2007 Mar 31;

Hernando-Harder AC, Franke A, Wedel T, Bottner M, Krammer HJ, Singer MV, Harder H. Intestinal Gas Retention in Patients with Idiopathic Slow-Transit Constipation. Dig Dis Sci. 2007 Mar 24;

Liebregts T, Adam B, Bredack C, Roth A, Heinzel S, Lester S, Downie-Doyle S, Smith E, Drew P, Talley NJ, Holtmann G. Immune activation in patients with irritable bowel syndrome. Gastroenterology. 2007 Mar;132(3):913-20.

Jiang J, Li N, Zhu WM, Li JS.  [Efficacy and safety of combined use of subtotalcolectomy and modified Duhamel procedure in the surgical treatment of severe functional constipation] Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Mar;10(2):115-8. Chinese.

Rao SS, Seaton K, Miller M, Brown K, Nygaard I, Stumbo P, Zimmerman B, Schulze K. Randomized controlled trial of biofeedback, sham feedback, and standard therapy for dyssynergic defecation. Clin Gastroenterol Hepatol. 2007 Mar;5(3):331-8.

Brusciano L, Limongelli P, del Genio G, Sansone S, Rossetti G, Maffettone V, Napoletano V, Sagnelli C, Amoroso A, Russo G, Pizza F, Del Genio A. Useful parameters helping proctologists to identify patients with defaecatory disorders that may be treated with pelvic floor rehabilitation. Tech Coloproctol. 2007 Mar;11(1):45-50.

Shafik A, Shafik I, El Sibai O, Shafik AA. Rectal cooling test in the differentiation between constipation due to rectal inertia and anismus. Tech Coloproctol. 2007 Mar;11(1):39-43.

Iantorno G, Bassotti G, Kogan Z, Lumi CM, Cabanne AM, Fisogni S, Varrica LM, Bilder CR, Munoz JP, Liserre B, Morelli A, Villanacci V. The enteric nervous system in chagasic and idiopathic megacolon. Am J Surg Pathol. 2007 Mar;31(3):460-8.

Di Palma JA, Cleveland MV, McGowan J, Herrera JL. An open-label study of chronic polyethylene glycol laxative use in chronic constipation. Aliment Pharmacol Ther. 2007 Mar 15;25(6):703-8.

Altomare DF, Rinaldi M, Rubini D, Rubini G, Portincasa P, Vacca M, Artor NA, Romano G, Memeo V. Long-Term Functional Assessment of Antegrade Colonic Enema for Combined Incontinence and Constipation Using a Modified Marsh and Kiff Technique. Dis Colon Rectum. 2007 Feb 15;

Sairanen U, Piirainen L, Nevala R, Korpela R. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Eur J Clin Nutr. 2007 Feb 14;

Lin SR, Ke MY, Luo JY, Yuan YZ, Wang JY, diTommaso S, Walter V, Huang J. A randomized, double-blind, placebo-controlled trial assessing the efficacy and safety of tegaserod in patients from China with chronic constipation. World J Gastroenterol. 2007 Feb 7;13(5):732-9.

Bassotti G, Villanacci V, Nascimbeni R, Asteria CR, Fisogni S, Nesi G, Legrenzi L, Mariano M, Tonelli F, Morelli A, Salerni B. Colonic neuropathological aspects in patients with intractable constipation due to obstructed defecation. Mod Pathol. 2007 Mar;20(3):367-74.

Holzer P. Treatment of opioid-induced gut dysfunction.
Expert Opin Investig Drugs. 2007 Feb;16(2):181-94. Review.

Gershon MD, Tack J. The serotonin signaling system: from basic understanding to drug development for functional GI disorders.
Gastroenterology. 2007 Jan;132(1):397-414. Review.

Hunt RH, Dhaliwal S, Tougas G, Pedro C, Labbe JF, Paul H, Ennamorato M. Prevalence, impact and attitudes toward lower gastrointestinal dysmotility and sensory symptoms, and their treatment in Canada: A descriptive study.
Can J Gastroenterol. 2007 Jan;21(1):31-7.

Murad-Regadas SM, Regadas FS, Rodrigues LV, Souza MH, Lima DM, Silva FR, Filho FS. A novel procedure to assess anismus using three-dimensional dynamic anal ultrasonography.
Colorectal Dis. 2007 Feb;9(2):159-65.

Dinning PG, Fuentealba SE, Kennedy ML, Lubowski DZ, Cook IJ. Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defecation frequency in patients with slow-transit constipation. Colorectal Dis. 2007 Feb;9(2):123-32.

Leung FW. Etiologic factors of chronic constipation: review of the scientific evidence. Dig Dis Sci. 2007 Feb;52(2):313-6.

Villanacci V, Bassotti G, Nascimbeni R, Cathomas G, Maurer CA, Fisogni S, Salerni B. Colonic lymphoid aggregates in slow transit constipation. Dig Dis Sci. 2007 Feb;52(2):321-3.

Costedio MM, Hyman N, Mawe GM. Serotonin and its role in colonic function and in gastrointestinal disorders.
Dis Colon Rectum. 2007 Mar;50(3):376-88.

Wald A. Chronic constipation: advances in management.
Neurogastroenterol Motil. 2007 Jan;19(1):4-10. Review.

Fried M, Johanson JF, Gwee KA, Wagner A, Pecher E, Rueegg P. Efficacy of tegaserod in chronic constipation in men. Am J Gastroenterol. 2007 Feb;102(2):362-70.

Poirier M, Abcarian H, Nelson R. Malone antegrade continent enema: an alternative to resection in severe defecation disorders.
Dis Colon Rectum. 2007 Jan;50(1):22-8.

Chan AO, Hui WM, Lam KF, Leung G, Yuen MF, Lam SK, Wong BC. Familial aggregation in constipated subjects in a tertiary referral center. Am J Gastroenterol. 2007 Jan;102(1):149-52.

Zutshi M, Hull TL, Trzcinski R, Arvelakis A, Xu M. Surgery for slow transit constipation: are we helping patients? Int J Colorectal Dis. 2007 Mar;22(3):265-9.

Zhang WQ, Yan GZ, Ye DD, Chen CW. Simultaneous assessment of the intraluminal pressure and transit time of the colon using a telemetry technique. Physiol Meas. 2007 Feb;28(2):141-8.

Renzi A, Izzo D, Di Sarno G, De Iuri A, Bucci L, Izzo G, Di Martino N. Cinedefecographic findings in patients with obstructed defecation sindrome. A study in 420 cases. Minerva Chir. 2006 Dec;61(6):493-9.

Peng HY, Xu AZ. Colonic exclusion and combined therapy for refractory constipation. World J Gastroenterol. 2006 Dec 28;12(48):7864-8.

Costedio MM, Hyman N, Mawe GM. Serotonin and Its Role in Colonic Function and in Gastrointestinal Disorders.
Dis Colon Rectum. 2006 Dec 29;

Pera M, Pares D, Pascual M, Perez M, Canete N, Sanchez de la Blanca MI, Andreu M, Grande L.  [Treatment of severe chronic constipation through the antegrade continent enema procedure.]
Cir Esp. 2006 Dec;80(6):403-5.

Hassan I, Pemberton JH, Young-Fadok TM, You YN, Drelichman ER, Rath-Harvey D, Schleck CD, Larson DR.  Ileorectal anastomosis for slow transit constipation: long-term functional and quality of life results. J Gastrointest Surg. 2006 Dec;10(10):1330-6;

Fried M, Johanson JF, Gwee KA, Wagner A, Pecher E, Rueegg P. Efficacy of Tegaserod in Chronic Constipation in Men. Am J Gastroenterol. 2006 Dec 11;

Lau PY, Fung B, Meng WC, Leung R, Yip AW, So SP, Lee QS, Chan D. Efficacy of multidisciplinary approach in treatment of constipation: a pilot study.
Hong Kong Med J. 2006 Dec;12(6):415-8.

Mortele KJ, Fairhurst J. Dynamic MR defecography of the posterior compartment: Indications, techniques and MRI features.
Eur J Radiol. 2006 Dec 2;

Chong VH, Jalihal A. Solitary rectal ulcer syndrome: characteristics, outcomes and predictive profiles for persistent bleeding per rectum. Singapore Med J. 2006 Dec;47(12):1063-8.

da Silva GM, Gurland B, Sleemi A, Levy G. Posterior vaginal wall prolapse does not correlate with fecal symptoms or objective measures of anorectal function. Am J Obstet Gynecol. 2006 Dec;195(6):1742-7.

Colecchia A, Vestito A, La Rocca A, Pasqui F, Nikiforaki A, Festi D. Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study. Minerva Gastroenterol Dietol. 2006 Dec;52(4):349-58.

Muller-Lissner S, Kamm MA, Musoglu A, Earnest DL, Dunger-Baldauf C, Shetzline MA. Safety, tolerability, and efficacy of tegaserod over 13 months in patients with chronic constipation.
Am J Gastroenterol. 2006 Nov;101(11):2558-69;

Miles CL, Fellowes D, Goodman ML, Wilkinson S. Laxatives for the management of constipation in palliative care patients.
Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003448. Review.

Houghton LA, Lea R, Agrawal A, Reilly B, Whorwell PJ. Relationship of abdominal bloating to distention in irritable bowel syndrome and effect of bowel habit. Gastroenterology. 2006 Oct;131(4):1003-10.

Di Stefano M, Miceli E, Missanelli A, Mazzocchi S, Tana P, Corazza GR. Role of colonic fermentation in the perception of colonic distention in irritable bowel syndrome and functional bloating. Clin Gastroenterol Hepatol. 2006 Oct;4(10):1242-7.

Bassotti G, Villanacci V, Cathomas G, Maurer CA, Fisogni S, Cadei M, Baron L, Morelli A, Valloncini E, Salerni B. Enteric neuropathology of the terminal ileum in patients with intractable slow-transit constipation. Hum Pathol. 2006 Oct;37(10):1252-8.

Bouchoucha M, Devroede G, Faye A, Le Toumelin P, Arhan P, Arsac M. Colonic response to food in constipation.
Int J Colorectal Dis. 2006 Dec;21(8):826-33. Epub 2005 Jun 21.

Houghton LA, Lea R, Agrawal A, Reilly B, Whorwell PJ. Relationship of abdominal bloating to distention in irritable bowel syndrome and effect of bowel habit. Gastroenterology. 2006 Oct;131(4):1003-10.

Di Stefano M, Miceli E, Missanelli A, Mazzocchi S, Tana P, Corazza GR. Role of colonic fermentation in the perception of colonic distention in irritable bowel syndrome and functional bloating. Clin Gastroenterol Hepatol. 2006 Oct;4(10):1242-7.

Christensen P, Bazzocchi G, Coggrave M, Abel R, Hultling C, Krogh K, Media S, Laurberg S. A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients. Gastroenterology. 2006 Sep;131(3):738-47.

Bassotti G, Villanacci V, Cathomas G, Maurer CA, Fisogni S, Cadei M, Baron L, Morelli A, Valloncini E, Salerni B. Enteric neuropathology of the terminal ileum in patients with intractable slow-transit constipation. Hum Pathol. 2006 Oct;37(10):1252-8.

Zutshi M, Hull TL, Trzcinski R, Arvelakis A, Xu M. Surgery for slow transit constipation: are we helping patients? Int J Colorectal Dis. 2006 Aug 31;

Bassotti G, Villanacci V. Slow transit constipation: a functional disorder becomes an enteric neuropathy. World J Gastroenterol. 2006 Aug 7;12(29):4609-13.

Ripetti V, Caputo D, Greco S, Alloni R, Coppola R. Is total colectomy the right choice in intractable slow-transit constipation?
Surgery. 2006 Sep;140(3):435-40.

Nahas SC, Habr-Gama A, Nahas CS, Araujo SE, Marques CF, Sobrado CW, Bocchini SF, Kiss DR. Surgical treatment of chagasic megacolon by abdominal rectosigmoidectomy with immediate posterior end-to-side stapling (Habr-Gama technique).